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Tdark
AAMDC
Mth938 domain-containing protein

Protein Summary
Description
May play a role in preadipocyte differentiation and adipogenesis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000393427
  • ENSP00000377078
  • ENSG00000087884
  • ENST00000526415
  • ENSP00000431808
  • ENST00000532481
  • ENSP00000433293

Symbol
  • C11orf67
  • CK067
  • PTD015
  • C11orf67
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.98
transcription factor
0.81
cell type or tissue
0.71
transcription factor binding site profile
0.71
cell line
0.63


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.98   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 144   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.98   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 144   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (24)
KCTD14
Tdark
Novelty:  1.19182828
Score:  0.688
Data Source:  STRINGDB
INTS4
Tdark
Novelty:  0.20868831
Score:  0.609
Data Source:  STRINGDB
USP35
Tbio
Family:  Enzyme
Novelty:  0.09341335
Score:  0.575
Data Source:  STRINGDB
NARS2
Tbio
Family:  Enzyme
Novelty:  0.01879317
Score:  0.542
Data Source:  STRINGDB
ALG8
Tbio
Family:  Enzyme
Novelty:  0.03721075
Score:  0.537
Data Source:  STRINGDB
AADACL3
Tdark
Family:  Enzyme
Novelty:  0.72455975
Score:  0.53
Data Source:  STRINGDB
BRWD1
Tbio
Family:  Epigenetic
Novelty:  0.09247334
Score:  0.505
Data Source:  STRINGDB
PRXL2C
Tdark
Novelty:  0.59489208
Score:  0.505
Data Source:  STRINGDB
RSF1
Tbio
Family:  Epigenetic
Novelty:  0.0155058
Score:  0.496
Data Source:  STRINGDB
RAB29
Tchem
Family:  Enzyme
Novelty:  0.03751616
Score:  0.495
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (4)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Sequence or structural Similarity (ISS)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
1
1
1
62.1
platelet count
1
1
1
49.5
sex hormone-binding globulin measurement
2
1
2
40.7
mean reticulocyte volume
1
1
1
33.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean platelet volume
1
62.1
platelet count
1
49.5
sex hormone-binding globulin measurement
2
40.7
mean reticulocyte volume
1
33.1
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
adipogenesis associated Mth938 domain containing
VGNC:11741
100607975
Mouse
MGI:1913523
66273
Rat
RGD:1561459
361606
Dog
adipogenesis associated Mth938 domain containing
VGNC:37411
102155803
Horse
adipogenesis associated Mth938 domain containing
VGNC:14889
100051441
Species
Name
OMA
EggNOG
Inparanoid
Chimp
adipogenesis associated Mth938 domain containing
Mouse
Rat
Dog
adipogenesis associated Mth938 domain containing
Horse
adipogenesis associated Mth938 domain containing
Publication Statistics
PubMed Score 4.98
PubMed score by year
PubTator Score 1.28
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title