Tbio RPF2 Ribosome production factor 2 homolog

Protein Summary

Description

Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus.

Uniprot Accession IDs

• Q9H7B2
• Q5VXN1
• Q8N4A1

Gene Name

• RPF2

Ensembl ID

• ENST00000441448
• ENSP00000402338
• ENSG00000197498

Symbol

• BXDC1
• BXDC1
• bA397G5.4

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.91
kinase perturbation	0.88
hub protein	0.85
interacting protein	0.82
transcription factor binding site profile	0.69

Protein Classes

PANTHER Classes

Protein / Nucleic Acid Binding / Nuclease / Ribosome Production Factor 2 Homolog

DTO Classes

Protein / Enzyme / Nuclease / Ribosome Production Factor 2 Homolog

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 31.72   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 155   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 31.72   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 155   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0