Tbio ELAC1 Zinc phosphodiesterase ELAC protein 1

Protein Summary

Description

Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

Uniprot Accession IDs

• Q9H777
• Q9NS99

Gene Name

• ELAC1

Ensembl ID

• ENST00000269466
• ENSP00000269466
• ENSG00000141642

Symbol

• D29
• D29

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cell type or tissue	0.8
histone modification site profile	0.64
microRNA	0.6
tissue sample	0.6
virus perturbation	0.55

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.52   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 216   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 18.52   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 216   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0