ALG9
Alpha-1,2-mannosyltransferase ALG9
Protein Summary
Catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides. This gene encodes an alpha-1,2-mannosyltransferase enzyme that functions in lipid-linked oligosaccharide assembly. Mutations in this gene result in congenital disorder of glycosylation type Il. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
- ENST00000398006
- ENSP00000381090
- ENSG00000086848
- ENST00000531154
- ENSP00000435517
- ENST00000614444
- ENSP00000484200
- ENST00000616540
- ENSP00000482437
- DIBD1
- CDG1L
- DIBD1
- GIKANIS
- LOH11CR1J
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
kinase perturbation | 0.96 | ||
virus perturbation | 0.68 | ||
transcription factor binding site profile | 0.64 | ||
cellular component | 0.6 | ||
pathway | 0.6 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 35.95 (req: < 5)
Gene RIFs: 8 (req: <= 3)
Antibodies: 57 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 35.95 (req: >= 5)
Gene RIFs: 8 (req: > 3)
Antibodies: 57 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0