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Tdark
WDCP
WD repeat and coiled-coil-containing protein

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000295148
  • ENSP00000295148
  • ENSG00000163026
  • ENST00000406895
  • ENSP00000385816

Symbol
  • C2orf44
  • MMAP
  • PP384
  • C2orf44
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.34   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 61   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.34   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 61   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (34)
RUVBL1
Tbio
Novelty:  0.0089115
p_int:  0.999997783
p_ni:  0.000002217
Score:  0.313
Data Source:  BioPlex,STRINGDB
RUVBL2
Tbio
Novelty:  0.01129017
p_int:  0.999996505
p_ni:  0.000003495
Score:  0.313
Data Source:  BioPlex,STRINGDB
SPATA1
Tdark
p_int:  0.999798371
p_ni:  0.000201629
Data Source:  BioPlex
CTBP1
Tbio
Novelty:  0.00243818
p_int:  0.999778492
p_ni:  0.000221508
Score:  0.18
Data Source:  BioPlex,STRINGDB
HIF1AN
Tbio
Novelty:  0.00861018
p_int:  0.999485163
p_ni:  0.00051483
p_wrong:  7e-9
Data Source:  BioPlex
PIP
Tbio
Novelty:  0.00208509
p_int:  0.999466613
p_ni:  0.000533387
Data Source:  BioPlex
PAPSS1
Tbio
Family:  Enzyme
Novelty:  0.01784751
p_int:  0.998527816
p_ni:  0.001472184
Score:  0.544
Data Source:  BioPlex,STRINGDB
GNA15
Tbio
Novelty:  0.00159196
p_int:  0.997997341
p_ni:  0.002002659
Score:  0.187
Data Source:  BioPlex,STRINGDB
INSYN2
Tdark
Novelty:  2.55244594
p_int:  0.997718995
p_ni:  0.002281005
Data Source:  BioPlex
EMILIN1
Tbio
Novelty:  0.02550566
p_int:  0.997583604
p_ni:  0.002416396
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (20)
Find Similar Targets
Items per page:
1 – 5 of 20
Data Source
Name
Explore in Pharos
Explore in Source
WikiPathways
Mesodermal Commitment Pathway
WikiPathways
Mesodermal Commitment Pathway
WikiPathways
Mesodermal Commitment Pathway
WikiPathways
Mesodermal Commitment Pathway
WikiPathways
ncRNAs involved in Wnt signaling in hepatocellular carcinoma
Name
Explore in Pharos
Explore in Source
Mesodermal Commitment Pathway
Mesodermal Commitment Pathway
Mesodermal Commitment Pathway
Mesodermal Commitment Pathway
ncRNAs involved in Wnt signaling in hepatocellular carcinoma
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Physical Interaction (IPI)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (26)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
reticulocyte count
7
5
14
95
reticulocyte measurement
3
5
8
90.7
lymphocyte count
4
4
5
90.4
HbA1c measurement
4
3
5
86.6
mean corpuscular volume
1
3
3
86.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
reticulocyte count
14
95
reticulocyte measurement
8
90.7
lymphocyte count
5
90.4
HbA1c measurement
5
86.6
mean corpuscular volume
3
86.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
WD repeat and coiled coil containing
VGNC:10287
737962
Macaque
WD repeat and coiled coil containing
703861
Mouse
MGI:3040699
238037
Rat
RGD:1563701
500623
Dog
WD repeat and coiled coil containing
VGNC:48344
610805
Species
Name
OMA
EggNOG
Inparanoid
Chimp
WD repeat and coiled coil containing
Macaque
WD repeat and coiled coil containing
Mouse
Rat
Dog
WD repeat and coiled coil containing
Publication Statistics
PubMed Score 4.34
PubMed score by year
PubTator Score 0.92
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title