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Tdark
ARMC7
Armadillo repeat-containing protein 7

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000245543
  • ENSP00000245543
  • ENSG00000125449
  • ENST00000581078
  • ENSP00000462962
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.8
transcription factor binding site profile
0.68
cell line
0.67
cell type or tissue
0.64
gene perturbation
0.62


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.73   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 68   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.73   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 68   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sex hormone-binding globulin measurement
4
1
4
80.9
lymphocyte count
1
1
1
66.3
lymphocyte percentage of leukocytes
2
2
2
55.2
C-reactive protein measurement
1
1
1
46.9
1
1
0
1.2
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sex hormone-binding globulin measurement
4
80.9
lymphocyte count
1
66.3
lymphocyte percentage of leukocytes
2
55.2
C-reactive protein measurement
1
46.9
0
1.2
21.5
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
armadillo repeat containing 7
VGNC:52093
107969322
Macaque
armadillo repeat containing 7
700833
Mouse
MGI:2679719
276905
Rat
RGD:1310043
287827
Dog
armadillo repeat containing 7
VGNC:51922
Species
Name
OMA
EggNOG
Inparanoid
Chimp
armadillo repeat containing 7
Macaque
armadillo repeat containing 7
Mouse
Rat
Dog
armadillo repeat containing 7
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9H6L4-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (36)
1 – 10 of 36
RBM48
Tdark
Novelty:  0.50797247
p_int:  0.999787158
p_wrong:  0.000212842
Score:  0.692
Data Source:  BioPlex,STRINGDB
NUP85
Tbio
Novelty:  0.02350514
Score:  0.739
Data Source:  STRINGDB
MRPL41
Tbio
Novelty:  0.04024303
Score:  0.733
Data Source:  STRINGDB
TRARG1
Tbio
Novelty:  0.07729433
Score:  0.696
Data Source:  STRINGDB
NALCN
Tchem
Family:  IC
Novelty:  0.01522178
Score:  0.661
Data Source:  STRINGDB
ZNF662
Tdark
Family:  TF
Novelty:  2.52868181
Score:  0.65
Data Source:  STRINGDB
FAM198A
Tdark
Novelty:  0.65293749
Score:  0.622
Data Source:  STRINGDB
DMAC1
Tbio
Novelty:  1.16519301
Score:  0.62
Data Source:  STRINGDB
MAEA
Tbio
Novelty:  0.00833813
Score:  0.616
Data Source:  STRINGDB
KLHDC4
Tdark
Novelty:  0.94196365
Score:  0.603
Data Source:  STRINGDB
Publication Statistics
PubMed Score  3.73

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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