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Tdark
ZNF385D
Zinc finger protein 385D

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000281523
  • ENSP00000281523
  • ENSG00000151789

Symbol
  • ZNF659
  • ZNF659
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
1
phenotype
0.8
tissue sample
0.62
disease
0.61
cell line
0.52


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.12   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 76   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.12   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 76   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mathematical ability
1
1
1
63.6
self reported educational attainment
1
1
1
63.6
cognitive function measurement
1
1
1
55.4
seasonal gut microbiome measurement
1
1
1
48
daytime rest measurement
1
1
1
40
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mathematical ability
1
63.6
self reported educational attainment
1
63.6
cognitive function measurement
1
55.4
seasonal gut microbiome measurement
1
48
daytime rest measurement
1
40
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 385D
VGNC:12251
460221
Macaque
zinc finger protein 385D
698852
Rat
RGD:1359606
305691
Dog
zinc finger protein 385D
VGNC:48716
477051
Horse
zinc finger protein 385D
VGNC:25313
100051873
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 385D
Macaque
zinc finger protein 385D
Rat
Dog
zinc finger protein 385D
Horse
zinc finger protein 385D
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9H6B1-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (3)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (36)
1 – 10 of 36
KIAA0895
Tdark
Novelty: 16.98666667
Score: 0.771
Data Source: STRINGDB
FAM19A1
Tdark
Novelty: 0.27533335
Score: 0.763
Data Source: STRINGDB
DPP10
Tbio
Family: Enzyme
Novelty: 0.02313473
Score: 0.642
Data Source: STRINGDB
NDST4
Tbio
Family: Enzyme
Novelty: 0.09591294
Score: 0.619
Data Source: STRINGDB
PITPNC1
Tbio
Novelty: 0.09338428
Score: 0.615
Data Source: STRINGDB
LDB2
Tbio
Novelty: 0.01621438
Score: 0.608
Data Source: STRINGDB
OR5H2
Tdark
Family: oGPCR
Novelty: 15.80588299
Score: 0.587
Data Source: STRINGDB
CEP162
Tdark
Novelty: 0.03171049
Score: 0.586
Data Source: STRINGDB
CPXM2
Tbio
Family: Enzyme
Novelty: 0.09967229
Score: 0.574
Data Source: STRINGDB
CMIP
Tbio
Novelty: 0.0076969
Score: 0.559
Data Source: STRINGDB
Publication Statistics
PubMed Score  3.12

PubMed score by year
PubTator Score  1.12

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer