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Tbio
PCIF1
Phosphorylated CTD-interacting factor 1

Protein Summary
Description
May play a role in transcription elongation or in coupling transcription to pre-mRNA processing through its association with the phosphorylated C-terminal domain (CTD) of RNAPII largest subunit.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000372409
  • ENSP00000361486
  • ENSG00000100982

Symbol
  • C20orf67
  • CAPAM
  • hCAPAM
  • hPCIF1
  • C20orf67
  • PPP1R121
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.91
histone modification site profile
0.81
transcription factor perturbation
0.8
transcription factor
0.7
tissue
0.65


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.44   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 69   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.44   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 69   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mathematical ability
3
2
3
92.6
1
1
0
1.2
79.9
mean corpuscular hemoglobin concentration
1
1
1
79
red blood cell density measurement
1
1
1
75.9
self reported educational attainment
1
1
1
72.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mathematical ability
3
92.6
0
1.2
79.9
mean corpuscular hemoglobin concentration
1
79
red blood cell density measurement
1
75.9
self reported educational attainment
1
72.4
Protein Data Bank (1)
1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Gene Ontology Terms (5)
Items per page:
10
1 – 4 of 4
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
HPA
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (33)
1 – 10 of 33
ERICH1
Tdark
Novelty: 1.30496362
Score: 0.684
Data Source: STRINGDB
PXDC1
Tdark
Novelty: 0.82453616
Score: 0.669
Data Source: STRINGDB
PSAPL1
Tdark
Novelty: 0.82322044
Score: 0.663
Data Source: STRINGDB
PDX1
Tbio
Family: TF
Novelty: 0.00232117
Score: 0.646
Data Source: STRINGDB
SLC22A23
Tbio
Family: Transporter
Novelty: 0.23405744
Score: 0.633
Data Source: STRINGDB
RSBN1L
Tdark
Novelty: 5.23364486
Score: 0.626
Data Source: STRINGDB
KATNAL1
Tbio
Family: Enzyme
Novelty: 0.11227609
Score: 0.592
Data Source: STRINGDB
STON2
Tbio
Novelty: 0.02098671
Score: 0.563
Data Source: STRINGDB
FBXO25
Tbio
Novelty: 0.1205608
Score: 0.557
Data Source: STRINGDB
TSC22D2
Tdark
Family: TF
Novelty: 0.30718123
Score: 0.557
Data Source: STRINGDB
Publication Statistics
PubMed Score  11.44

PubMed score by year
PubTator Score  5.42

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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