SAV1
Protein salvador homolog 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.91 | ||
histone modification site profile | 0.77 | ||
virus perturbation | 0.76 | ||
transcription factor binding site profile | 0.69 | ||
disease perturbation | 0.68 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Signal Transduction | ||||
Reactome | Signaling by Hippo | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Signal Transduction | ||||
Signaling by Hippo | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean platelet volume | 3 | 5 | 5 | 98.2 | |||||
Dupuytren Contracture | 1 | 1 | 0 | 1.2 | 68.6 | ||||
platelet count | 1 | 2 | 2 | 68.4 | |||||
serum alanine aminotransferase measurement | 1 | 1 | 0 | 6.9 | 52.4 | ||||
balding measurement | 1 | 1 | 1 | 35 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean platelet volume | 5 | 98.2 | |||||
Dupuytren Contracture | 0 | 1.2 | 68.6 | ||||
platelet count | 2 | 68.4 | |||||
serum alanine aminotransferase measurement | 0 | 6.9 | 52.4 | ||||
balding measurement | 1 | 35 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | salvador family WW domain containing protein 1 | VGNC:12527 | 452899 | |||||
Macaque | salvador family WW domain containing protein 1 | 706424 | ||||||
Mouse | MGI:1927144 | 64010 | ||||||
Rat | RGD:1307253 | 299116 | ||||||
Dog | salvador family WW domain containing protein 1 | VGNC:45877 | 480319 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | salvador family WW domain containing protein 1 | |||||
Macaque | salvador family WW domain containing protein 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | salvador family WW domain containing protein 1 | |||||
PMID | Year | Title |
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