You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
RWDD1
RWD domain-containing protein 1

Protein Summary
Description
Protects DRG2 from proteolytic degradation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000466444
  • ENSP00000420357
  • ENSG00000111832
  • ENST00000487832
  • ENSP00000428778

Symbol
  • DFRP2
  • CGI-24
  • PTD013
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.88
transcription factor binding site profile
0.83
virus perturbation
0.83
histone modification site profile
0.7
disease perturbation
0.68


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.28   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 114   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.28   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 114   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Data Bank (1)
1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Gene Ontology Terms (8)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
Ensembl
Protein-Protein Interactions (40)
1 – 10 of 40
DRG2
Tbio
Novelty: 0.03367003
p_int: 1
Score: 0.992
Data Source: BioPlex,STRINGDB
DRG1
Tbio
Novelty: 0.31168831
Score: 0.928
Data Source: STRINGDB
ZC3H15
Tbio
Novelty: 0.16901408
Score: 0.899
Data Source: STRINGDB
GCN1
Tbio
Novelty: 0.03715937
Score: 0.85
Data Source: STRINGDB
PFDN5
Tbio
Novelty: 0.09272547
Score: 0.693
Data Source: STRINGDB
CLVS2
Tbio
Novelty: 1.875
Score: 0.688
Data Source: STRINGDB
RWDD4
Tdark
Novelty: 0.6
Score: 0.682
Data Source: STRINGDB
HSPBP1
Tbio
Novelty: 0.01599246
Score: 0.676
Data Source: STRINGDB
UBL7
Tdark
Novelty: 0.30057803
Score: 0.669
Data Source: STRINGDB
EBNA1BP2
Tbio
Novelty: 0.02554881
Score: 0.666
Data Source: STRINGDB
Publication Statistics
PubMed Score  3.28

PubMed score by year
PubTator Score  0.2

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer