Tbio RWDD1 RWD domain-containing protein 1

Protein Summary

Description

Protects DRG2 from proteolytic degradation.

Uniprot Accession IDs

• Q9H446
• A8K3W2
• A8MT24
• Q9Y313
• Q9Y6B3

Gene Name

• RWDD1

Ensembl ID

• ENST00000466444
• ENSP00000420357
• ENSG00000111832
• ENST00000487832
• ENSP00000428778

Symbol

• DFRP2
• CGI-24
• PTD013

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.88
transcription factor binding site profile	0.83
virus perturbation	0.83
histone modification site profile	0.7
disease perturbation	0.68

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.91   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 114   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.91   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 114   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0