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Tbio
TMPRSS5
Transmembrane protease serine 5

Protein Summary
Description
May play a role in hearing. This gene encodes a protein that belongs to the serine protease family. Serine proteases are known to be involved in many physiological and pathological processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000299882
  • ENSP00000299882
  • ENSG00000166682
  • ENST00000643074
  • ENSP00000495454

Symbol
  • SPINESIN
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
cell type or tissue
0.82
PubMedID
0.66
cell line
0.63
tissue sample
0.54


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.22   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 287   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.22   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 287   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0