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Tbio
CDIP1
Cell death-inducing p53-target protein 1

Protein Summary
Description
Acts as an important p53/TP53-apoptotic effector. Regulates TNF-alpha-mediated apoptosis in a p53/TP53-dependent manner.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000399599
  • ENSP00000382508
  • ENSG00000089486
  • ENST00000562334
  • ENSP00000455050
  • ENST00000563332
  • ENSP00000454994
  • ENST00000563507
  • ENSP00000455462
  • ENST00000567695
  • ENSP00000457877
  • ENST00000611166
  • ENSP00000480842
  • ENSG00000274336
  • ENST00000631859
  • ENSP00000488843
  • ENST00000632680
  • ENSP00000488474
  • ENST00000632937
  • ENSP00000488066
  • ENST00000633324
  • ENSP00000487657

Symbol
  • C16orf5
  • CDIP
  • LITAFL
  • I1
  • CDIP
  • LITAFL
  • C16orf5
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.84
transcription factor
0.77
transcription factor binding site profile
0.77
gene perturbation
0.75
cell type or tissue
0.58


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 64.29   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 74   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 64.29   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 74   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (40)
1 – 10 of 40
SNRNP25
Tdark
Novelty:  0.5951307
Score:  0.796
Data Source:  STRINGDB
DESI1
Tdark
Family:  Enzyme
Novelty:  0.27035255
Score:  0.714
Data Source:  STRINGDB
UBE2O
Tbio
Novelty:  0.07084123
Score:  0.714
Data Source:  STRINGDB
NPRL3
Tbio
Family:  Enzyme
Novelty:  0.0110744
Score:  0.707
Data Source:  STRINGDB
UBB
Tbio
Novelty:  0.00661254
Score:  0.695
Data Source:  STRINGDB
UBC
Tbio
Novelty:  0.00204643
Score:  0.69
Data Source:  STRINGDB
RHBDF2
Tbio
Family:  Enzyme
Novelty:  0.02487334
Score:  0.68
Data Source:  STRINGDB
DDX47
Tbio
Family:  Enzyme
Novelty:  0.08694078
Score:  0.665
Data Source:  STRINGDB
POLR3K
Tbio
Family:  Enzyme
Novelty:  0.07105011
Score:  0.656
Data Source:  STRINGDB
MGRN1
Tbio
Family:  Enzyme
Novelty:  0.04981605
Score:  0.645
Data Source:  STRINGDB
Gene Ontology Terms (7)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
GWAS Traits (20)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sex hormone-binding globulin measurement
6
3
6
89.1
BMI-adjusted waist-hip ratio
7
4
8
88.6
waist-hip ratio
4
4
5
76
triglyceride measurement
2
2
2
72.4
BMI-adjusted hip circumference
1
2
2
69.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sex hormone-binding globulin measurement
6
89.1
BMI-adjusted waist-hip ratio
8
88.6
waist-hip ratio
5
76
triglyceride measurement
2
72.4
BMI-adjusted hip circumference
2
69.6
Find similar targets by:
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
cell death inducing p53 target 1
VGNC:13681
453881
Mouse
MGI:1913876
66626
Rat
RGD:1310686
360480
Dog
cell death inducing p53 target 1
VGNC:39041
490025
Horse
cell death inducing p53 target 1
VGNC:16337
100069792
Species
Name
OMA
EggNOG
Inparanoid
Chimp
cell death inducing p53 target 1
Mouse
Rat
Dog
cell death inducing p53 target 1
Horse
cell death inducing p53 target 1
Publication Statistics
PubMed Score 64.29
PubMed score by year
PubTator Score 15.08
PubTator score by year