DHX36
ATP-dependent DNA/RNA helicase DHX36
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 1 | ||
protein domain | 0.92 | ||
virus perturbation | 0.88 | ||
kinase perturbation | 0.84 | ||
cell type or tissue | 0.79 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cytosolic sensors of pathogen-associated DNA | ||||
Reactome | DEx/H-box helicases activate type I IFN and inflammatory cytokines production | ||||
Reactome | Immune System | ||||
Reactome | Innate Immune System | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cytosolic sensors of pathogen-associated DNA | ||||
DEx/H-box helicases activate type I IFN and inflammatory cytokines production | ||||
Immune System | ||||
Innate Immune System | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
body mass index | 4 | 3 | 4 | 86.3 | |||||
2 | 2 | 2 | 75.7 | ||||||
apolipoprotein A 1 measurement | 1 | 1 | 1 | 53.3 | |||||
comparative body size at age 10, self-reported | 1 | 1 | 1 | 52 | |||||
high density lipoprotein cholesterol measurement | 1 | 1 | 1 | 39.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
body mass index | 4 | 86.3 | |||||
2 | 75.7 | ||||||
apolipoprotein A 1 measurement | 1 | 53.3 | |||||
comparative body size at age 10, self-reported | 1 | 52 | |||||
high density lipoprotein cholesterol measurement | 1 | 39.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | DEAH-box helicase 36 | VGNC:7057 | 460791 | |||||
Macaque | DEAH-box helicase 36 | 708112 | ||||||
Mouse | MGI:1919412 | 72162 | ||||||
Rat | RGD:1308767 | 310461 | ||||||
Dog | DEAH-box helicase 36 | VGNC:39946 | 477117 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | DEAH-box helicase 36 | |||||
Macaque | DEAH-box helicase 36 | |||||
Mouse | ||||||
Rat | ||||||
Dog | DEAH-box helicase 36 | |||||
PMID | Year | Title |
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