PPIL3
Peptidyl-prolyl cis-trans isomerase-like 3
Protein Summary
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing. This gene encodes a member of the cyclophilin family. Cyclophilins catalyze the cis-trans isomerization of peptidylprolyl imide bonds in oligopeptides. They have been proposed to act either as catalysts or as molecular chaperones in protein-folding events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2008]
- ENST00000286175
- ENSP00000286175
- ENSG00000240344
- ENST00000392283
- ENSP00000376107
- ENST00000409449
- ENSP00000387012
- CYPJ
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
histone modification site profile | 0.92 | ||
transcription factor binding site profile | 0.83 | ||
kinase perturbation | 0.66 | ||
tissue sample | 0.62 | ||
small molecule perturbation | 0.61 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 12.62 (req: < 5)
Gene RIFs: 7 (req: <= 3)
Antibodies: 208 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 12.62 (req: >= 5)
Gene RIFs: 7 (req: > 3)
Antibodies: 208 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0