HSD3B7
3 beta-hydroxysteroid dehydrogenase type 7
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor | 0.75 | ||
kinase perturbation | 0.71 | ||
tissue sample | 0.65 | ||
histone modification site profile | 0.6 | ||
pathway | 0.56 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Bile acid and bile salt metabolism | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of lipids | ||||
Reactome | Metabolism of steroids | ||||
Reactome | Synthesis of bile acids and bile salts | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Bile acid and bile salt metabolism | ||||
Metabolism | ||||
Metabolism of lipids | ||||
Metabolism of steroids | ||||
Synthesis of bile acids and bile salts | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Traceable Author Statement (TAS) | Reactome | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
4 | 4 | 0 | 1.2 | 83.8 | |||||
mean reticulocyte volume | 1 | 1 | 1 | 82.8 | |||||
mean corpuscular volume | 1 | 1 | 1 | 82.2 | |||||
response to anticoagulant | 1 | 1 | 0 | 20.4 | 81 | ||||
triglyceride measurement | 2 | 2 | 1 | 2.1 | 68.1 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
0 | 1.2 | 83.8 | |||||
mean reticulocyte volume | 1 | 82.8 | |||||
mean corpuscular volume | 1 | 82.2 | |||||
response to anticoagulant | 0 | 20.4 | 81 | ||||
triglyceride measurement | 1 | 2.1 | 68.1 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | VGNC:13757 | 454059 | |||||
Mouse | MGI:2141879 | 101502 | ||||||
Dog | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | VGNC:41811 | 489917 | |||||
Horse | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | VGNC:18890 | 100063491 | |||||
Cow | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | VGNC:29978 | 540229 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | |||||
Mouse | ||||||
Dog | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | |||||
Horse | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | |||||
Cow | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | |||||
PMID | Year | Title |
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