SLC26A1
Sulfate anion transporter 1
Protein Summary
Mediates sulfate transport with high affinity (PubMed:12713736). Mediates oxalate transport (PubMed:12713736). Mediates bicarbonate transport (By similarity). Does not accept succinate as cosubstrate (By similarity). This gene is a member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures, but have markedly different tissue expression patterns. This gene is primarily expressed in the liver, pancreas, and brain. Three splice variants that encode different isoforms have been identified. [provided by RefSeq, Jul 2008]
- ENST00000361661
- ENSP00000354721
- ENSG00000145217
- ENST00000398516
- ENSP00000381528
- ENST00000398520
- ENSP00000381532
- ENST00000622731
- ENSP00000483506
- SAT1
- CAON
- EDM4
- SAT1
- SAT-1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
pathway | 0.99 | ||
protein domain | 0.85 | ||
virus perturbation | 0.76 | ||
biological process | 0.74 | ||
molecular function | 0.73 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 38.43 (req: < 5)
Gene RIFs: 10 (req: <= 3)
Antibodies: 93 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 38.43 (req: >= 5)
Gene RIFs: 10 (req: > 3)
Antibodies: 93 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 12
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0