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Tbio
SH3BGRL3
SH3 domain-binding glutamic acid-rich-like protein 3

Protein Summary
Description
Could act as a modulator of glutaredoxin biological activity.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000270792
  • ENSP00000270792
  • ENSG00000142669

Symbol
  • TIP-B1
  • SH3BP-1
  • HEL-S-297
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.87
transcription factor perturbation
0.8
transcription factor binding site profile
0.77
kinase perturbation
0.71
gene perturbation
0.68


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.76   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 129   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.76   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 129   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0