You are using an outdated browser. Please upgrade your browser to improve your experience.

Tchem
LPAR5
Lysophosphatidic acid receptor 5

Protein Summary
Description
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. This gene encodes a member of the rhodopsin class of G protein-coupled transmembrane receptors. This protein transmits extracellular signals from lysophosphatidic acid to cells through heterotrimeric G proteins and mediates numerous cellular processes. Many G protein receptors serve as targets for pharmaceutical drugs. Transcript variants of this gene have been described.[provided by RefSeq, Dec 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000329858
  • ENSP00000327875
  • ENSG00000184574
  • ENST00000431922
  • ENSP00000393098

Symbol
  • GPR92
  • GPR93
  • LPA5
  • GPR92
  • GPR93
  • KPG_010
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.61
microRNA
0.58
transcription factor
0.53
cell type or tissue
0.45
metabolite
0.45


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 65.51   (req: < 5)
Gene RIFs: 14   (req: <= 3)
Antibodies: 181   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 65.51   (req: >= 5)
Gene RIFs: 14   (req: > 3)
Antibodies: 181   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 81
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0