Tbio STMN4 Stathmin-4

Protein Summary

Description

Exhibits microtubule-destabilizing activity.

Uniprot Accession IDs

• Q9H169
• B7Z2Z7
• B7Z4I9
• D3DSS8
• D3DSS9
• G5EA16
• Q2TAB9

Gene Name

• STMN4

Ensembl ID

• ENST00000265770
• ENSP00000265770
• ENSG00000015592
• ENST00000350889
• ENSP00000342538
• ENST00000519997
• ENSP00000428474
• ENST00000523048
• ENSP00000428428

Symbol

• RB3

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.71
PubMedID	0.64
gene perturbation	0.53
disease perturbation	0.49
transcription factor	0.46

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.77   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 145   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.77   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 145   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0