FXYD6
FXYD domain-containing ion transport regulator 6
Protein Summary
This gene encodes a member of the FXYD family of transmembrane proteins. This particular protein encodes phosphohippolin, which likely affects the activity of Na,K-ATPase. Multiple alternatively spliced transcript variants encoding the same protein have been described. Related pseudogenes have been identified on chromosomes 10 and X. Read-through transcripts have been observed between this locus and the downstream sodium/potassium-transporting ATPase subunit gamma (FXYD2, GeneID 486) locus.[provided by RefSeq, Feb 2011]
- ENST00000260282
- ENSP00000260282
- ENSG00000137726
- ENST00000524656
- ENSP00000431427
- ENST00000526014
- ENSP00000433312
- ENST00000527717
- ENSP00000431446
- ENST00000530956
- ENSP00000463158
- ENST00000539526
- ENSP00000442756
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
PubMedID | 0.87 | ||
gene perturbation | 0.85 | ||
transcription factor perturbation | 0.8 | ||
tissue sample | 0.64 | ||
tissue | 0.59 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 23.99 (req: < 5)
Gene RIFs: 11 (req: <= 3)
Antibodies: 113 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 23.99 (req: >= 5)
Gene RIFs: 11 (req: > 3)
Antibodies: 113 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0