CSTF2T
Cleavage stimulation factor subunit 2 tau variant
Protein Classes
Protein Summary
May play a significant role in AAUAAA-independent mRNA polyadenylation in germ cells. Directly involved in the binding to pre-mRNAs (By similarity).
- ENST00000331173
- ENSP00000332444
- ENSG00000177613
- KIAA0689
- CstF-64T
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
kinase perturbation | 0.93 | ||
disease perturbation | 0.9 | ||
virus perturbation | 0.9 | ||
transcription factor binding site profile | 0.88 | ||
histone modification site profile | 0.8 | ||
Related Tools
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 11.99 (req: < 5)
Gene RIFs: 7 (req: <= 3)
Antibodies: 179 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 11.99 (req: >= 5)
Gene RIFs: 7 (req: > 3)
Antibodies: 179 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
GWAS Traits (1)
Items per page:
1 – 1 of 1
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
self reported educational attainment | 1 | 1 | 1 | 14.2 | |||||
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1 – 1 of 1
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
self reported educational attainment | 1 | 14.2 | |||||
Orthologs (5)
1 – 5 of 5
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Mouse | MGI:1932622 | 83410 | ||||||
Rat | RGD:1310026 | 309338 | ||||||
Horse | cleavage stimulation factor subunit 2 tau variant | VGNC:16921 | 100062520 | |||||
Cow | cleavage stimulation factor subunit 2 tau variant | VGNC:27782 | 783569 | |||||
Pig | cleavage stimulation factor subunit 2 tau variant | 100157243 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Mouse | ||||||
Rat | ||||||
Horse | cleavage stimulation factor subunit 2 tau variant | |||||
Cow | cleavage stimulation factor subunit 2 tau variant | |||||
Pig | cleavage stimulation factor subunit 2 tau variant | |||||
Protein Structure (0 Structures, 1 AlphaFold Model)
Pathways (12)
Reactome (10)
KEGG (1)
WikiPathways (1)
Click on a row in the table to change the structure displayed.
Items per page:
1 – 5 of 10
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Gene expression (Transcription) | ||||
Reactome | Metabolism of RNA | ||||
Reactome | Processing of Capped Intron-Containing Pre-mRNA | ||||
Reactome | Processing of Capped Intronless Pre-mRNA | ||||
Reactome | Processing of Intronless Pre-mRNAs | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Gene expression (Transcription) | ||||
Metabolism of RNA | ||||
Processing of Capped Intron-Containing Pre-mRNA | ||||
Processing of Capped Intronless Pre-mRNA | ||||
Processing of Intronless Pre-mRNAs | ||||
Gene Ontology Terms (9)
Functions (2)
Components (3)
Processes (4)
Items per page:
10
1 – 2 of 2
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Protein-Protein Interactions (241)
1 – 10 of 241
CSTF3
Novelty: 0.05260909
p_int: 0.999999998
p_ni: 2e-9
Score: 0.999
Data Source: BioPlex,Reactome,STRINGDB
CSTF2
Novelty: 0.01389909
p_int: 0.999999961
p_ni: 3.9e-8
Score: 0.988
Data Source: BioPlex,STRINGDB
CSTF1
Novelty: 0.08711712
p_int: 0.999999775
p_ni: 1.57e-7
p_wrong: 6.8e-8
Score: 0.998
Data Source: BioPlex,Reactome,STRINGDB
SYMPK
Novelty: 0.01773552
p_int: 0.999949385
p_ni: 0.000050614
p_wrong: 1e-9
Score: 0.994
Data Source: BioPlex,STRINGDB
BIRC2
Novelty: 0.00199701
p_int: 0.993715602
p_ni: 0.006284398
Score: 0.151
Data Source: BioPlex,STRINGDB
CLINT1
Novelty: 0.00945381
p_int: 0.992242443
p_ni: 0.007757528
p_wrong: 2.9e-8
Data Source: BioPlex
CRTAP
Novelty: 0.02380647
p_int: 0.991074611
p_ni: 0.008925389
Score: 0.416
Data Source: BioPlex,STRINGDB
CRYAA
Novelty: 0.01914081
p_int: 0.990913988
p_ni: 0.008636504
p_wrong: 0.000449507
Data Source: BioPlex
CPEB1
Novelty: 0.00444378
p_int: 0.990658461
p_ni: 0.009340764
p_wrong: 7.75e-7
Score: 0.822
Data Source: BioPlex,STRINGDB
ZNF571
Family: TF
Novelty: 58
p_int: 0.988349588
p_ni: 0.011063641
p_wrong: 0.000586771
Score: 0.329
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score 11.99
PubMed score by year
PubTator Score 3.19
PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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UniProt Keyword
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