You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
CSTF2T
Cleavage stimulation factor subunit 2 tau variant

Protein Summary
Description
May play a significant role in AAUAAA-independent mRNA polyadenylation in germ cells. Directly involved in the binding to pre-mRNAs (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000331173
  • ENSP00000332444
  • ENSG00000177613

Symbol
  • KIAA0689
  • CstF-64T
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.93
disease perturbation
0.9
virus perturbation
0.9
transcription factor binding site profile
0.88
histone modification site profile
0.8


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.99   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 179   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.99   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 179   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
1
1
14.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
14.2
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1932622
83410
Rat
RGD:1310026
309338
Horse
cleavage stimulation factor subunit 2 tau variant
VGNC:16921
100062520
Cow
cleavage stimulation factor subunit 2 tau variant
VGNC:27782
783569
Pig
cleavage stimulation factor subunit 2 tau variant
100157243
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Horse
cleavage stimulation factor subunit 2 tau variant
Cow
cleavage stimulation factor subunit 2 tau variant
Pig
cleavage stimulation factor subunit 2 tau variant
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9H0L4-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (12)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 10
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Metabolism of RNA
Reactome
Processing of Capped Intron-Containing Pre-mRNA
Reactome
Processing of Capped Intronless Pre-mRNA
Reactome
Processing of Intronless Pre-mRNAs
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Metabolism of RNA
Processing of Capped Intron-Containing Pre-mRNA
Processing of Capped Intronless Pre-mRNA
Processing of Intronless Pre-mRNAs
Gene Ontology Terms (9)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (241)
1 – 10 of 241
CSTF3
Tbio
Novelty:  0.05260909
p_int:  0.999999998
p_ni:  2e-9
Score:  0.999
Data Source:  BioPlex,Reactome,STRINGDB
CSTF2
Tbio
Novelty:  0.01389909
p_int:  0.999999961
p_ni:  3.9e-8
Score:  0.988
Data Source:  BioPlex,STRINGDB
CSTF1
Tbio
Novelty:  0.08711712
p_int:  0.999999775
p_ni:  1.57e-7
p_wrong:  6.8e-8
Score:  0.998
Data Source:  BioPlex,Reactome,STRINGDB
SYMPK
Tbio
Novelty:  0.01773552
p_int:  0.999949385
p_ni:  0.000050614
p_wrong:  1e-9
Score:  0.994
Data Source:  BioPlex,STRINGDB
BIRC2
Tchem
Novelty:  0.00199701
p_int:  0.993715602
p_ni:  0.006284398
Score:  0.151
Data Source:  BioPlex,STRINGDB
CLINT1
Tbio
Novelty:  0.00945381
p_int:  0.992242443
p_ni:  0.007757528
p_wrong:  2.9e-8
Data Source:  BioPlex
CRTAP
Tbio
Novelty:  0.02380647
p_int:  0.991074611
p_ni:  0.008925389
Score:  0.416
Data Source:  BioPlex,STRINGDB
CRYAA
Tchem
Novelty:  0.01914081
p_int:  0.990913988
p_ni:  0.008636504
p_wrong:  0.000449507
Data Source:  BioPlex
CPEB1
Tbio
Novelty:  0.00444378
p_int:  0.990658461
p_ni:  0.009340764
p_wrong:  7.75e-7
Score:  0.822
Data Source:  BioPlex,STRINGDB
ZNF571
Tdark
Family:  TF
Novelty:  58
p_int:  0.988349588
p_ni:  0.011063641
p_wrong:  0.000586771
Score:  0.329
Data Source:  BioPlex,STRINGDB
Publication Statistics
PubMed Score  11.99

PubMed score by year
PubTator Score  3.19

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer