Tdark CCDC113 Coiled-coil domain-containing protein 113

Protein Summary

Description

Component of centriolar satellites contributing to primary cilium formation.

Uniprot Accession IDs

• Q9H0I3
• B2RAQ7
• B4DR20
• Q9NZX2

Gene Name

• CCDC113

Ensembl ID

• ENST00000219299
• ENSP00000219299
• ENSG00000103021
• ENST00000443128
• ENSP00000402588

Symbol

• HSPC065

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.92
histone modification site profile	0.83
tissue	0.59
microRNA	0.51
transcription factor binding site profile	0.48

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.65   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 80   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.65   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 80   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0