Tbio CRISPLD2 Cysteine-rich secretory protein LCCL domain-containing 2

Protein Summary

Description

Promotes matrix assembly.

Uniprot Accession IDs

• Q9H0B8
• D3DUM0
• Q6P590
• Q6UWH0
• Q6UXC6
• Q96IB1
• Q96K61

Gene Name

• CRISPLD2

Ensembl ID

• ENST00000262424
• ENSP00000262424
• ENSG00000103196
• ENST00000564567
• ENSP00000457655
• ENST00000569090
• ENSP00000454858

Symbol

• CRISP11
• LCRISP2
• LGL1
• CRISP11
• LCRISP2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.97
gene perturbation	0.9
small molecule perturbation	0.8
PubMedID	0.65
tissue	0.64

Protein Classes

PANTHER Classes

Protein / Defense/immunity Protein / Cysteine-rich Secretory Protein Lccl Domain-containing 2

DTO Classes

Protein / Immune Response / Cysteine-rich Secretory Protein Lccl Domain-containing 2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 40.24   (req: < 5)

Gene RIFs: 22   (req: <= 3)

Antibodies: 123   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 40.24   (req: >= 5)

Gene RIFs: 22   (req: > 3)

Antibodies: 123   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0