You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
ZMYND15
Zinc finger MYND domain-containing protein 15

Protein Summary
Description
Acts as a transcriptional repressor through interaction with histone deacetylases (HDACs). May be important for spermiogenesis. This gene encodes a MYND-containing zinc-binding protein with a nuclear localization sequence. A similar gene in mice has been shown to act as a testis-specific transcriptional repressor by recruiting histone deacetylase enzymes to regulate spatiotemporal expression of many haploid genes. This protein may play an important role in spermatogenesis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jun 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000269289
  • ENSP00000269289
  • ENSG00000141497
  • ENST00000433935
  • ENSP00000391742
  • ENST00000573751
  • ENSP00000459501
  • ENST00000592813
  • ENSP00000465435

Symbol
  • SPGF14
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.97
cell type or tissue
0.76
tissue sample
0.69
histone modification site profile
0.66
biological process
0.59


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.86   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 16   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.86   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 16   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0