IL22
Interleukin-22
Protein Summary
Cytokine that contributes to the inflammatory response in vivo. This gene is a member of the IL10 family of cytokines that mediate cellular inflammatory responses. The encoded protein functions in antimicrobial defense at mucosal surfaces and in tissue repair. This protein also has pro-inflammatory properties and plays a role in in the pathogenesis of several intestinal diseases. [provided by RefSeq, Jul 2018]
- ENST00000328087
- ENSP00000329384
- ENSG00000127318
- ENST00000538666
- ENSP00000442424
- ILTIF
- ZCYTO18
- TIFa
- IL-21
- IL-22
- ILTIF
- IL-TIF
- IL-D110
- zcyto18
- TIFIL-23
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
biological term | 0.96 | ||
phenotype | 0.79 | ||
protein domain | 0.58 | ||
small molecule perturbation | 0.58 | ||
disease | 0.56 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 588.43 (req: < 5)
Gene RIFs: 383 (req: <= 3)
Antibodies: 876 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 588.43 (req: >= 5)
Gene RIFs: 383 (req: > 3)
Antibodies: 876 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0