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Tbio
ZNF350
Zinc finger protein 350

Protein Summary
Description
Transcriptional repressor. Binds to a specific sequence, 5'-GGGxxxCAGxxxTTT-3', within GADD45 intron 3.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000243644
  • ENSP00000243644
  • ENSG00000256683

Symbol
  • ZBRK1
  • ZFQR
  • ZBRK1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.81
tissue
0.68
histone modification site profile
0.63
cell line
0.62
protein domain
0.58


Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.25   (req: < 5)
Gene RIFs: 29   (req: <= 3)
Antibodies: 192   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 22.25   (req: >= 5)
Gene RIFs: 29   (req: > 3)
Antibodies: 192   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 11
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 350
VGNC:11548
456257
Macaque
zinc finger protein 350
719864
Dog
zinc finger protein 350
VGNC:49701
111098961
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 350
Macaque
zinc finger protein 350
Dog
zinc finger protein 350
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9GZX5-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (9)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 8
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
Metabolism of proteins
Reactome
Post-translational protein modification
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
Metabolism of proteins
Post-translational protein modification
RNA Polymerase II Transcription
Gene Ontology Terms (16)
Items per page:
10
1 – 7 of 7
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
NTNU_SB
Inferred from Direct Assay (IDA)
NTNU_SB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence Alignment (ISA)
NTNU_SB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (29)
1 – 10 of 29
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
p_int:  0.996941441
p_ni:  0.003058559
Score:  0.976
Data Source:  BioPlex,Reactome,STRINGDB
CDK8
Tchem
Family:  Kinase
Novelty:  0.00508026
p_int:  0.944865964
p_ni:  0.055134032
p_wrong:  4e-9
Data Source:  BioPlex
SUMO1
Tbio
Novelty:  0.00137629
Score:  0.932
Data Source:  Reactome,STRINGDB
UBE2I
Tbio
Novelty:  0.00267883
Score:  0.929
Data Source:  Reactome,STRINGDB
RNF11
Tbio
Novelty:  0.04766714
Score:  0.923
Data Source:  STRINGDB
GADD45A
Tbio
Novelty:  0.00178533
Score:  0.74
Data Source:  STRINGDB
BRCA1
Tchem
Novelty:  0.00011146
Score:  0.733
Data Source:  STRINGDB
RBBP8
Tbio
Family:  Enzyme
Novelty:  0.0044233
Score:  0.731
Data Source:  STRINGDB
BRIP1
Tbio
Novelty:  0.03886334
Score:  0.63
Data Source:  STRINGDB
ATXN2
Tbio
Novelty:  0.00373116
Score:  0.609
Data Source:  STRINGDB
Publication Statistics
PubMed Score  22.25

PubMed score by year
PubTator Score  20.11

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer