MS4A7
Membrane-spanning 4-domains subfamily A member 7
Protein Summary
May be involved in signal transduction as a component of a multimeric receptor complex. This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
- ENST00000300184
- ENSP00000300184
- ENSG00000166927
- ENST00000358246
- ENSP00000350983
- ENST00000534016
- ENSP00000434637
- 4SPAN2
- CD20L4
- CFFM4
- CFFM4
- MS4A8
- 4SPAN2
- CD20L4
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
PubMedID | 0.76 | ||
tissue sample | 0.74 | ||
microRNA | 0.59 | ||
virus perturbation | 0.55 | ||
tissue | 0.49 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.83 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 130 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 1.83 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 130 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 0
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0