Tchem NMUR2 Neuromedin-U receptor 2

Protein Summary

Description

Receptor for the neuromedin-U and neuromedin-S neuropeptides. This gene encodes a protein from the G-protein coupled receptor 1 family. This protein is a receptor for neuromedin U, which is a neuropeptide that is widely distributed in the gut and central nervous system. This receptor plays an important role in the regulation of food intake and body weight. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q9GZQ4
• Q7LC54
• Q96AM5
• Q9NRA6
• NMU-R2

Gene Name

• NMUR2

Ensembl ID

• ENST00000255262
• ENSP00000255262
• ENSG00000132911

Symbol

• NMU2R
• TGR1
• FM4
• FM-4
• TGR1
• NMU2R
• TGR-1
• NMU-R2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	1
biological process	0.77
gene perturbation	0.71
protein domain	0.58
microRNA	0.53

Protein Classes

PANTHER Classes

Protein / Receptor / G-protein Coupled Receptor / Neuromedin-u Receptor 2

DTO Classes

Protein / G-protein Coupled Receptor / Class A Rhodopsin Like / Neuromedin U Receptor / Neuromedin-u Receptor 2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 114.29   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 177   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 114.29   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 177   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 22

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 71

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0