GPR88
Probable G-protein coupled receptor 88
Protein Summary
Probable G-protein coupled receptor implicated in a large repertoire of behavioral responses that engage motor activities, spatial learning, and emotional processing. May play a role in the regulation of cognitive and motor function. The protein encoded by this gene is a G protein-coupled receptor found almost exclusively in the striatum, a brain structure that controls motor function and cognition. Defects in this gene have been associated with chorea, speech delay, and learning difficulties, as well as some neuropsychiatric disorders. [provided by RefSeq, Mar 2017]
- ENST00000315033
- ENSP00000314223
- ENSG00000181656
- STRG
- STRG
- COCPMR
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
microRNA | 0.72 | ||
tissue sample | 0.6 | ||
cell type or tissue | 0.57 | ||
gene perturbation | 0.56 | ||
tissue | 0.54 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 65.35 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 193 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 65.35 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 193 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 9
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligands: 107
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0