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Tbio
YIPF3
Protein YIPF3

Protein Summary
Description
Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000372422
  • ENSP00000361499
  • ENSG00000137207

Symbol
  • C6orf109
  • KLIP1
  • KLIP1
  • FinGER3
  • C6orf109
  • dJ337H4.3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.9
kinase perturbation
0.88
cell type or tissue
0.72
transcription factor binding site profile
0.71
disease perturbation
0.68


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.94   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 107   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.94   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 107   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glomerular filtration rate
1
2
2
58.2
mathematical ability
2
1
2
56.6
creatinine measurement
1
2
2
55.8
platelet count
1
1
1
52.7
BMI-adjusted hip circumference
1
1
1
28.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glomerular filtration rate
2
58.2
mathematical ability
2
56.6
creatinine measurement
2
55.8
platelet count
1
52.7
BMI-adjusted hip circumference
1
28.1
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
Yip1 domain family member 3
VGNC:3791
472240
Macaque
Yip1 domain family member 3
700228
Mouse
MGI:106280
28064
Rat
RGD:1308185
301245
Dog
Yip1 domain family member 3
VGNC:48489
481817
Species
Name
OMA
EggNOG
Inparanoid
Chimp
Yip1 domain family member 3
Macaque
Yip1 domain family member 3
Mouse
Rat
Dog
Yip1 domain family member 3
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9GZM5-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (6)
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
LIFEdb
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (131)
1 – 10 of 131
SLC22A5
Tbio
Family:  Transporter
Novelty:  0.00290828
p_int:  0.999999633
p_ni:  3.67e-7
Data Source:  BioPlex
SLC43A1
Tbio
Family:  Transporter
Novelty:  0.06939259
p_int:  0.999998836
p_ni:  8.29e-7
p_wrong:  3.35e-7
Data Source:  BioPlex
MGAT4B
Tbio
Family:  Enzyme
Novelty:  0.11244606
p_int:  0.99999705
p_ni:  0.00000294
p_wrong:  1e-8
Data Source:  BioPlex
RETREG2
Tdark
Novelty:  0.18851807
p_int:  0.999992948
p_ni:  0.000007032
p_wrong:  2e-8
Data Source:  BioPlex
CAV1
Tbio
Novelty:  0.00035244
p_int:  0.999975774
p_ni:  0.000024226
Data Source:  BioPlex
ERGIC2
Tbio
Novelty:  0.08610944
p_int:  0.999920169
p_ni:  0.000079831
Data Source:  BioPlex
ENDOD1
Tdark
Family:  Enzyme
Novelty:  0.26430864
p_int:  0.999916403
p_ni:  0.000083594
p_wrong:  3e-9
Data Source:  BioPlex
PIGN
Tbio
Family:  Enzyme
Novelty:  0.02210783
p_int:  0.999897104
p_ni:  0.000102839
p_wrong:  5.6e-8
Data Source:  BioPlex
REEP4
Tbio
Novelty:  0.37950931
p_int:  0.999891426
p_ni:  0.000108574
Data Source:  BioPlex
NIPA2
Tbio
Novelty:  0.05451663
p_int:  0.999874409
p_ni:  0.000036721
p_wrong:  0.000088869
Score:  0.181
Data Source:  BioPlex,STRINGDB
Publication Statistics
PubMed Score  6.94

PubMed score by year
PubTator Score  11.83

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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