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Tchem
DCLK3
Serine/threonine-protein kinase DCLK3

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000416516
  • ENSP00000394484
  • ENSG00000163673

Symbol
  • DCAMKL3
  • DCDC3C
  • KIAA1765
  • CLR
  • DCK3
  • DCDC3C
  • DCAMKL3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.9
protein domain
0.85
small molecule
0.75
microRNA
0.68
tissue sample
0.66


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 292   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 87   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 292   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 87   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 2
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drugs: 2
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (6)
Dark Kinase Knowledgebase
Thumbnail image for Dark Kinase Knowledgebase
The Dark Kinase Knowledgebase is an an online compendium of knowledge and experimental results of understudied kinases.
ProKinO
Thumbnail image for ProKinO
The ProKinO is a protein kinase-specific ontology, which provides a controlled vocabulary of terms, their hierarchy, and relationships unifying sequence, structure, function, mutation and pathway information on kinases.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (34)
DCDC2B
Tdark
Novelty:  1.63648312
Score:  0.811
Data Source:  STRINGDB
SHOC2
Tbio
Novelty:  0.01203957
Score:  0.757
Data Source:  STRINGDB
STK31
Tchem
Family:  Kinase
Novelty:  0.12405945
Score:  0.691
Data Source:  STRINGDB
RP1L1
Tbio
Novelty:  0.02385711
Score:  0.688
Data Source:  STRINGDB
KIFC3
Tbio
Novelty:  0.0662353
Score:  0.683
Data Source:  STRINGDB
TBRG4
Tbio
Novelty:  0.03556613
Score:  0.674
Data Source:  STRINGDB
DCDC2
Tbio
Novelty:  0.00395729
Score:  0.667
Data Source:  STRINGDB
PPP1R9B
Tbio
Novelty:  0.00676121
Score:  0.664
Data Source:  STRINGDB
SMCHD1
Tbio
Novelty:  0.01383021
Score:  0.653
Data Source:  STRINGDB
MAPK8IP2
Tbio
Family:  Enzyme
Novelty:  0.01788453
Score:  0.638
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (15)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
schizophrenia
11
6
4
1.1
92.7
9
2
4
1.1
87.5
3
3
2
1.1
78.4
educational attainment
1
1
1
64.5
2
2
2
62.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
schizophrenia
4
1.1
92.7
4
1.1
87.5
2
1.1
78.4
educational attainment
1
64.5
2
62.8
Find similar targets by:
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
doublecortin like kinase 3
VGNC:11379
470787
Macaque
doublecortin like kinase 3
699654
Mouse
MGI:3039580
245038
Rat
RGD:1309232
316023
Dog
doublecortin like kinase 3
VGNC:39805
485581
Species
Name
OMA
EggNOG
Inparanoid
Chimp
doublecortin like kinase 3
Macaque
doublecortin like kinase 3
Mouse
Rat
Dog
doublecortin like kinase 3
Publication Statistics
PubMed Score 292.00
PubMed score by year
PubTator Score 39.96
PubTator score by year
Patents
Patents by year
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Related Publications
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PMID
Year
Title