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Tbio
FOXQ1
Forkhead box protein Q1

Protein Summary
Description
Plays a role in hair follicle differentiation. FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called the forkhead or winged helix domain. FOX genes are involved in embryonic development, cell cycle regulation, tissue-specific gene expression, cell signaling, and tumorigenesis (Bieller et al., 2001 [PubMed 11747606]).[supplied by OMIM, May 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000296839
  • ENSP00000296839
  • ENSG00000164379

Symbol
  • HFH1
  • HFH1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.93
PubMedID
0.82
tissue sample
0.77
transcription factor binding site profile
0.72
histone modification site profile
0.68


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 49.73   (req: < 5)
Gene RIFs: 43   (req: <= 3)
Antibodies: 438   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 49.73   (req: >= 5)
Gene RIFs: 43   (req: > 3)
Antibodies: 438   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Pathways (7)
Items per page:
1 – 5 of 7
Data Source
Name
Explore in Pharos
Explore in Source
WikiPathways
Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
WikiPathways
Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
WikiPathways
ncRNAs involved in Wnt signaling in hepatocellular carcinoma
WikiPathways
Preimplantation Embryo
WikiPathways
Wnt Signaling
Name
Explore in Pharos
Explore in Source
Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
ncRNAs involved in Wnt signaling in hepatocellular carcinoma
Preimplantation Embryo
Wnt Signaling
Gene Ontology Terms (8)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Sequence Alignment (ISA)
NTNU_SB
Inferred from Electronic Annotation (IEA)
Ensembl
Inferred from Electronic Annotation (IEA)
Ensembl
Protein-Protein Interactions (31)
1 – 10 of 31
NACC1
Tbio
Novelty: 0.04840662
Score: 0.69
Data Source: STRINGDB
ZFAND3
Tbio
Novelty: 0.18016694
Score: 0.662
Data Source: STRINGDB
TPPP
Tbio
Novelty: 0.01032069
Score: 0.645
Data Source: STRINGDB
GMDS
Tbio
Family: Enzyme
Novelty: 0.00474944
Score: 0.632
Data Source: STRINGDB
HOXC13
Tbio
Family: TF
Novelty: 0.02179648
Score: 0.629
Data Source: STRINGDB
CDH1
Tbio
Novelty: 0.0001303
Score: 0.619
Data Source: STRINGDB
MESP1
Tbio
Family: TF
Novelty: 0.03830197
Score: 0.568
Data Source: STRINGDB
TWIST1
Tbio
Family: TF
Novelty: 0.0011524
Score: 0.562
Data Source: STRINGDB
APOBR
Tbio
Novelty: 0.09162308
Score: 0.56
Data Source: STRINGDB
TCF15
Tbio
Family: TF
Novelty: 0.00068197
Score: 0.559
Data Source: STRINGDB
Publication Statistics
PubMed Score  49.73

PubMed score by year
PubTator Score  39.51

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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