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Tbio
TSGA10
Testis-specific gene 10 protein

Protein Summary
Description
Plays a role in spermatogenesis (PubMed:28905369). When overexpressed, prevents nuclear localization of HIF1A (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000355053
  • ENSP00000347161
  • ENSG00000135951
  • ENST00000393483
  • ENSP00000377123
  • ENST00000410001
  • ENSP00000386956

Symbol
  • CEP4L
  • CT79
  • CEP4L
  • SPGF26
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.9
transcription factor binding site profile
0.87
transcription factor
0.8
tissue sample
0.71
cell type or tissue
0.59


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 28   (req: < 5)
Gene RIFs: 9   (req: <= 3)
Antibodies: 127   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 28   (req: >= 5)
Gene RIFs: 9   (req: > 3)
Antibodies: 127   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
reticulocyte measurement
2
2
3
81.6
reticulocyte count
2
2
3
80
intelligence
1
1
1
24.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
reticulocyte measurement
3
81.6
reticulocyte count
3
80
intelligence
1
24.5
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
testis specific 10
VGNC:1937
459436
Mouse
MGI:2685063
211484
Rat
RGD:621142
252923
Dog
testis specific 10
VGNC:47899
474561
Horse
testis specific 10
VGNC:51421
100060456
Species
Name
OMA
EggNOG
Inparanoid
Chimp
testis specific 10
Mouse
Rat
Dog
testis specific 10
Horse
testis specific 10
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9BZW7-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (5)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
Ensembl
Inferred from Electronic Annotation (IEA)
Ensembl
Protein-Protein Interactions (39)
1 – 10 of 39
TSGA10IP
Tdark
Novelty:  20.75428866
Score:  0.735
Data Source:  STRINGDB
FBXO39
Tbio
Novelty:  0.05342001
Score:  0.706
Data Source:  STRINGDB
ODF4
Tbio
Novelty:  0.13423621
Score:  0.687
Data Source:  STRINGDB
SOX30
Tbio
Family:  TF
Novelty:  0.04791535
Score:  0.65
Data Source:  STRINGDB
BACE1
Tchem
Family:  Enzyme
Novelty:  0.00042175
Score:  0.628
Data Source:  STRINGDB
SPATA19
Tbio
Novelty:  0.06203122
Score:  0.61
Data Source:  STRINGDB
PPP1R32
Tdark
Family:  Enzyme
Novelty:  0.38056479
Score:  0.589
Data Source:  STRINGDB
LIPT1
Tdark
Family:  Enzyme
Novelty:  0.0546324
Score:  0.561
Data Source:  STRINGDB
ROPN1L
Tbio
Novelty:  0.18077695
Score:  0.553
Data Source:  STRINGDB
CINP
Tbio
Family:  Enzyme
Novelty:  0.07004715
Score:  0.552
Data Source:  STRINGDB
Publication Statistics
PubMed Score  28.00

PubMed score by year
PubTator Score  14.89

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer