PUS3
tRNA pseudouridine(38/39) synthase
Protein Summary
Formation of pseudouridine at position 39 in the anticodon stem and loop of transfer RNAs. The protein encoded by this gene catalyzes the formation of tRNA pseudouridine from tRNA uridine at position 39 in the anticodon stem and loop of transfer RNAs. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
- ENST00000227474
- ENSP00000227474
- ENSG00000110060
- ENST00000530811
- ENSP00000432386
- MRT55
- FKSG32
- 2610020J05Rik
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
kinase perturbation | 0.98 | ||
histone modification site profile | 0.88 | ||
protein domain | 0.73 | ||
transcription factor binding site profile | 0.68 | ||
disease perturbation | 0.56 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 42.7 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 82 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 42.7 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 82 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0