You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
LDHAL6B
L-lactate dehydrogenase A-like 6B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000307144
  • ENSP00000302393
  • ENSG00000171989

Symbol
  • LDHAL6
  • LDHL
  • LDHL
  • LDH6B
  • LDHAL6
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.92
gene perturbation
0.76
tissue sample
0.55
pathway
0.51
cell line
0.48


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 120.04   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 125   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 120.04   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 125   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum metabolite measurement
1
1
2
56
pulse pressure measurement
1
1
1
46.9
platelet crit
1
1
1
33.1
body height
1
1
1
29
phosphatidylethanolamine measurement
1
1
1
26.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum metabolite measurement
2
56
pulse pressure measurement
1
46.9
platelet crit
1
33.1
body height
1
29
phosphatidylethanolamine measurement
1
26.1
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
lactate dehydrogenase A like 6B
VGNC:10257
747141
Species
Name
OMA
EggNOG
Inparanoid
Chimp
lactate dehydrogenase A like 6B
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9BYZ2-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (50)
Metabolism (R-HSA-1430728)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism
Reactome
Pyruvate metabolism
Reactome
Pyruvate metabolism and Citric Acid (TCA) cycle
Reactome
The citric acid (TCA) cycle and respiratory electron transport
Name
Explore in Pharos
Explore in Source
Metabolism
Pyruvate metabolism
Pyruvate metabolism and Citric Acid (TCA) cycle
The citric acid (TCA) cycle and respiratory electron transport
Gene Ontology Terms (5)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
Reactome
Protein-Protein Interactions (116)
1 – 10 of 116
APBB2
Tbio
Novelty:  0.06546724
p_int:  0.989942761
p_ni:  0.008579854
p_wrong:  0.001477385
Score:  0.188
Data Source:  BioPlex,STRINGDB
MTIF2
Tbio
Novelty:  0.06681774
p_int:  0.989389979
p_ni:  0.010610021
Score:  0.291
Data Source:  BioPlex,STRINGDB
DNLZ
Tdark
Novelty:  0.10113346
p_int:  0.982796594
p_ni:  0.017163412
p_wrong:  0.000039995
Score:  0.265
Data Source:  BioPlex,STRINGDB
LDHD
Tbio
Family:  Enzyme
Novelty:  0.0230704
Score:  0.963
Data Source:  STRINGDB
ME2
Tbio
Novelty:  0.03635548
Score:  0.946
Data Source:  STRINGDB
GOT1
Tbio
Family:  Enzyme
Novelty:  0.00448817
Score:  0.944
Data Source:  STRINGDB
PC
Tbio
Family:  Enzyme
Novelty:  0.00271694
Score:  0.94
Data Source:  STRINGDB
PKLR
Tbio
Family:  Kinase
Novelty:  0.00268398
Score:  0.93
Data Source:  STRINGDB
GOT2
Tbio
Family:  Enzyme
Novelty:  0.00054023
Score:  0.922
Data Source:  STRINGDB
GPI
Tbio
Family:  Enzyme
Novelty:  0.00095404
Score:  0.917
Data Source:  STRINGDB
Publication Statistics
PubMed Score  120.04

PubMed score by year
PubTator Score  6.39

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer