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Tdark
MRPL9
39S ribosomal protein L9, mitochondrial

Protein Summary
Description
This is a nuclear gene encoding a protein component of the 39S subunit of the mitochondrial ribosome. Alternative splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Jul 2014]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000368830
  • ENSP00000357823
  • ENSG00000143436

Symbol
  • L9mt
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
co-expressed gene
1
kinase perturbation
1
histone modification site profile
0.93
transcription factor perturbation
0.88
interacting protein
0.83


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 175   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 175   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (226)
MRPL30
Tdark
Novelty:  1.03623556
p_int:  0.99842963
p_ni:  0.00157037
Score:  0.992
Data Source:  BioPlex,STRINGDB
MRPL47
Tbio
Novelty:  0.05648009
p_int:  0.997735965
p_ni:  0.002264035
Score:  0.997
Data Source:  BioPlex,STRINGDB
MRPS30
Tbio
Novelty:  0.08115544
p_int:  0.997289511
p_ni:  0.002710489
Score:  0.996
Data Source:  BioPlex,STRINGDB
MRPL53
Tdark
Novelty:  1.0076471
p_int:  0.996675245
p_ni:  0.003324755
Score:  0.995
Data Source:  BioPlex,STRINGDB
MRPL18
Tbio
Novelty:  0.73438796
p_int:  0.995918038
p_ni:  0.004081961
p_wrong:  2e-9
Score:  0.999
Data Source:  BioPlex,STRINGDB
MRPL13
Tbio
Novelty:  0.04173503
p_int:  0.994725943
p_ni:  0.005274051
p_wrong:  6e-9
Score:  0.999
Data Source:  BioPlex,STRINGDB
RPL37
Tbio
Novelty:  0.03935854
p_int:  0.981299971
p_ni:  0.018700029
Score:  0.345
Data Source:  BioPlex,STRINGDB
GNL3
Tbio
Novelty:  0.00886703
p_int:  0.965194859
p_ni:  0.034805141
Score:  0.213
Data Source:  BioPlex,STRINGDB
MRPL10
Tbio
Novelty:  0.27087019
p_int:  0.954300616
p_ni:  0.045699384
Score:  0.989
Data Source:  BioPlex,STRINGDB
H1FNT
Tdark
Novelty:  0.05593238
p_int:  0.948197092
p_ni:  0.051802908
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (7)
Metabolism of proteins (R-HSA-392499)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 6
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of proteins
Reactome
Mitochondrial translation
Reactome
Mitochondrial translation elongation
Reactome
Mitochondrial translation initiation
Reactome
Mitochondrial translation termination
Name
Explore in Pharos
Explore in Source
Metabolism of proteins
Mitochondrial translation
Mitochondrial translation elongation
Mitochondrial translation initiation
Mitochondrial translation termination
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (16)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum gamma-glutamyl transferase measurement
2
1
2
81.7
2
3
0
1.1
77.1
vitamin D measurement
1
2
2
73.6
Eczema
1
1
0
1.1
73.5
1
1
0
1.1
73.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum gamma-glutamyl transferase measurement
2
81.7
0
1.1
77.1
vitamin D measurement
2
73.6
Eczema
0
1.1
73.5
0
1.1
73.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
mitochondrial ribosomal protein L9
VGNC:1331
457301
Macaque
mitochondrial ribosomal protein L9
711235
Mouse
MGI:2137211
78523
Rat
RGD:1359171
310653
Horse
mitochondrial ribosomal protein L9
VGNC:50854
100060037
Species
Name
OMA
EggNOG
Inparanoid
Chimp
mitochondrial ribosomal protein L9
Macaque
mitochondrial ribosomal protein L9
Mouse
Rat
Horse
mitochondrial ribosomal protein L9
Publication Statistics
PubMed Score 3.00
PubMed score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title