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Tbio
PECR
Peroxisomal trans-2-enoyl-CoA reductase

Protein Summary
Description
Participates in chain elongation of fatty acids. Has no 2,4-dienoyl-CoA reductase activity.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000265322
  • ENSP00000265322
  • ENSG00000115425

Symbol
  • SDR29C1
  • TERP
  • DCRRP
  • PVIARL
  • HPDHASE
  • SDR29C1
  • HSA250303
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.94
virus perturbation
0.92
kinase perturbation
0.81
histone modification site profile
0.8
interacting protein
0.77


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 69.52   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 159   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 69.52   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 159   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (93)
TRIB1
Tbio
Family:  Kinase
Novelty:  0.01587891
p_int:  0.99999989
p_ni:  1.1e-7
Score:  0.202
Data Source:  BioPlex,STRINGDB
HNRNPF
Tbio
Novelty:  0.01833966
p_int:  0.999997584
p_ni:  0.000002416
Score:  0.189
Data Source:  BioPlex,STRINGDB
POMGNT2
Tbio
Family:  Enzyme
Novelty:  0.15109569
p_int:  0.999997014
p_ni:  0.000002956
p_wrong:  3e-8
Score:  0.188
Data Source:  BioPlex,STRINGDB
UBE2E3
Tbio
Novelty:  0.03477232
p_int:  0.999996006
p_ni:  0.000003978
p_wrong:  1.7e-8
Score:  0.184
Data Source:  BioPlex,STRINGDB
HENMT1
Tdark
Family:  Enzyme
Novelty:  0.17427834
p_int:  0.999993169
p_ni:  0.000002609
p_wrong:  0.000004222
Score:  0.205
Data Source:  BioPlex,STRINGDB
CDPF1
Tdark
Novelty:  0.85714286
p_int:  0.999992447
p_ni:  0.000007551
p_wrong:  2e-9
Data Source:  BioPlex
RNF181
Tbio
Family:  Enzyme
Novelty:  0.27482636
p_int:  0.999515809
p_ni:  0.000173957
p_wrong:  0.000310234
Data Source:  BioPlex
LCN1
Tbio
Novelty:  0.00510137
p_int:  0.998688093
p_ni:  0.001311907
Score:  0.513
Data Source:  BioPlex,STRINGDB
UBA5
Tbio
Novelty:  0.05089296
p_int:  0.997951849
p_ni:  0.002048151
Score:  0.261
Data Source:  BioPlex,STRINGDB
ACY1
Tbio
Family:  Enzyme
Novelty:  0.00912344
p_int:  0.928388137
p_ni:  0.071611863
Score:  0.313
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (12)
Alpha-oxidation of phytanate (R-HSA-389599)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 7
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Alpha-oxidation of phytanate
Reactome
Fatty acid metabolism
Reactome
Metabolism
Reactome
Metabolism of lipids
Reactome
Peroxisomal lipid metabolism
Name
Explore in Pharos
Explore in Source
Alpha-oxidation of phytanate
Fatty acid metabolism
Metabolism
Metabolism of lipids
Peroxisomal lipid metabolism
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
1
49.5
1
1
0
1.4
24.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
49.5
0
1.4
24.5
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
peroxisomal trans-2-enoyl-CoA reductase
VGNC:2752
459929
Macaque
peroxisomal trans-2-enoyl-CoA reductase
695174
Mouse
MGI:2148199
111175
Rat
RGD:70925
113956
Dog
peroxisomal trans-2-enoyl-CoA reductase
VGNC:44411
478901
Species
Name
OMA
EggNOG
Inparanoid
Chimp
peroxisomal trans-2-enoyl-CoA reductase
Macaque
peroxisomal trans-2-enoyl-CoA reductase
Mouse
Rat
Dog
peroxisomal trans-2-enoyl-CoA reductase
Publication Statistics
PubMed Score 69.52
PubMed score by year
PubTator Score 19.26
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title