Tbio TEX101 Testis-expressed protein 101

Protein Summary

Description

Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct (By similarity). May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity).

Uniprot Accession IDs

• Q9BY14
• Q7L5R2
• Q9BPY7

Gene Name

• TEX101

Ensembl ID

• ENST00000598265
• ENSP00000472769
• ENSG00000131126
• ENST00000602198
• ENSP00000472308

Symbol

• SGRG
• SGRG
• CT131
• GTPR867
• NYD-SP8
• PRO1884
• SPATA44
• TES101RP

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.81
cellular component	0.71
gene perturbation	0.63
cell type or tissue	0.62
cell line	0.54

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 39.6   (req: < 5)

Gene RIFs: 11   (req: <= 3)

Antibodies: 36   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 39.6   (req: >= 5)

Gene RIFs: 11   (req: > 3)

Antibodies: 36   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0