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Tchem
EBPL
Emopamil-binding protein-like

Protein Classes
Protein Summary
Description
Does not possess sterol isomerase activity and does not bind sigma ligands.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000242827
  • ENSP00000242827
  • ENSG00000123179
  • ENST00000378268
  • ENSP00000367516
  • ENST00000378270
  • ENSP00000367519
  • ENST00000378272
  • ENSP00000367521

Symbol
  • EBRP
  • ERP
  • EBRP
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.94
kinase perturbation
0.88
histone modification site profile
0.83
cell type or tissue
0.68
transcription factor perturbation
0.61


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.44   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 64   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.44   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 64   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 1
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drugs: 2
Active Ligands (1)
1 – 1 of 1
CHEMBL2314420
chemical structure image
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
emopamil binding protein like
VGNC:7286
452721
Macaque
emopamil binding protein like
706833
Mouse
MGI:1915427
68177
Rat
RGD:1304571
361054
Dog
EBP like
VGNC:40179
476910
Species
Name
OMA
EggNOG
Inparanoid
Chimp
emopamil binding protein like
Macaque
emopamil binding protein like
Mouse
Rat
Dog
EBP like
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9BY08-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (5)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (26)
1 – 10 of 26
ALG11
Tbio
Family: Enzyme
Novelty: 0.00872486
Score: 0.667
Data Source: STRINGDB
SPRYD7
Tdark
Novelty: 0.25334319
Score: 0.588
Data Source: STRINGDB
DLEU7
Tdark
Novelty: 0.08581635
Score: 0.555
Data Source: STRINGDB
ARL11
Tbio
Family: Enzyme
Novelty: 0.04033783
Score: 0.473
Data Source: STRINGDB
CAB39L
Tbio
Novelty: 0.15875148
Score: 0.473
Data Source: STRINGDB
KCNRG
Tbio
Novelty: 0.09992793
Score: 0.472
Data Source: STRINGDB
TMUB2
Tdark
Novelty: 1.76302035
Score: 0.469
Data Source: STRINGDB
RASGEF1C
Tdark
Novelty: 0.93266395
Score: 0.459
Data Source: STRINGDB
HCFC2
Tbio
Novelty: 0.12260416
Score: 0.454
Data Source: STRINGDB
DHCR7
Tchem
Family: Enzyme
Novelty: 0.00358937
Score: 0.454
Data Source: STRINGDB
Publication Statistics
PubMed Score  4.44

PubMed score by year
PubTator Score  0.64

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer