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Tdark
MAK16
Protein MAK16 homolog

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IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.47   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 47   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.47   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 47   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
MAK16 homolog
VGNC:848
472734
Macaque
MAK16 homolog
696648
Mouse
MGI:1915170
67920
Rat
RGD:1311297
306526
Dog
MAK16 homolog
VGNC:42932
475593
Species
Name
OMA
EggNOG
Inparanoid
Chimp
MAK16 homolog
Macaque
MAK16 homolog
Mouse
Rat
Dog
MAK16 homolog
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9BXY0-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (4)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Protein-Protein Interactions (310)
1 – 10 of 310
RPF1
Tdark
Novelty: 3.67047505
p_int: 0.999999969
p_ni: 3.1e-8
Score: 0.994
Data Source: BioPlex,STRINGDB
FRMD6
Tbio
Novelty: 0.0034642
p_int: 0.999999793
p_ni: 2.07e-7
Score: 0.152
Data Source: BioPlex,STRINGDB
WDR74
Tbio
Novelty: 0.07119796
p_int: 0.999999285
p_ni: 7.15e-7
Score: 0.991
Data Source: BioPlex,STRINGDB
TUBA8
Tbio
Novelty: 0.06454549
p_int: 0.999994476
p_ni: 0.000005524
Data Source: BioPlex
RRP1
Tbio
Novelty: 0.12984245
p_int: 0.999946515
p_ni: 0.000053485
Score: 0.978
Data Source: BioPlex,STRINGDB
NOC2L
Tbio
Novelty: 0.00226536
p_int: 0.999678911
p_ni: 0.000321061
p_wrong: 2.9e-8
Score: 0.958
Data Source: BioPlex,STRINGDB
NOC3L
Tbio
Novelty: 0.05635731
p_int: 0.999671752
p_ni: 0.000328248
Score: 0.986
Data Source: BioPlex,STRINGDB
RPS27A
Tbio
Novelty: 0.00658124
p_int: 0.999468191
p_ni: 0.000531809
Score: 0.162
Data Source: BioPlex,STRINGDB
RPL26L1
Tdark
Novelty: 0.75408617
p_int: 0.997490724
p_ni: 0.002509276
Score: 0.509
Data Source: BioPlex,STRINGDB
CEBPZ
Tbio
Novelty: 0.00861664
p_int: 0.997101024
p_ni: 0.002898976
Score: 0.897
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  12.47

PubMed score by year
PubTator Score  2.28

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
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