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Tbio
NUSAP1
Nucleolar and spindle-associated protein 1

Protein Summary
Description
Microtubule-associated protein with the capacity to bundle and stabilize microtubules (By similarity). May associate with chromosomes and promote the organization of mitotic spindle microtubules around them. NUSAP1 is a nucleolar-spindle-associated protein that plays a role in spindle microtubule organization (Raemaekers et al., 2003 [PubMed 12963707]).[supplied by OMIM, Jun 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000260359
  • ENSP00000260359
  • ENSG00000137804
  • ENST00000414849
  • ENSP00000400746
  • ENST00000450592
  • ENSP00000401014
  • ENST00000559596
  • ENSP00000453403
  • ENST00000560177
  • ENSP00000453657
  • ENST00000560747
  • ENSP00000454097

Symbol
  • ANKT
  • LNP
  • ANKT
  • SAPL
  • BM037
  • NUSAP
  • Q0310
  • PRO0310p1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.98
kinase perturbation
0.96
histone modification site profile
0.89
co-expressed gene
0.82
transcription factor binding site profile
0.77


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 92.72   (req: < 5)
Gene RIFs: 38   (req: <= 3)
Antibodies: 216   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 92.72   (req: >= 5)
Gene RIFs: 38   (req: > 3)
Antibodies: 216   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0