GGTLC1
Glutathione hydrolase light chain 1
Protein Summary
This gene encodes a member of the gamma-glutamyl transpeptidase (GGT) family, which are important in the metabolism of glutathione. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. In contrast, the product of this gene only contains homology to the light chain region, and lacks a transmembrane domain. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2008]
- ENST00000278765
- ENSP00000278765
- ENSG00000149435
- ENST00000286890
- ENSP00000286890
- ENST00000335694
- ENSP00000337587
- GGTLA4
- GGTL6
- GGTLA3
- GGTLA4
- dJ831C21.1
- dJ831C21.2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
cell type or tissue | 0.8 | ||
cell line | 0.58 | ||
tissue sample | 0.42 | ||
chemical | 0.41 | ||
protein complex | 0.4 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 10.59 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 63 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 10.59 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 63 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0