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Tdark
LSM14B
Protein LSM14 homolog B

Protein Summary
Description
May play a role in control of mRNA translation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000279068
  • ENSP00000279068
  • ENSG00000149657

Symbol
  • C20orf40
  • FAM61B
  • RAP55B
  • FT005
  • LSM13
  • FAM61B
  • RAP55B
  • C20orf40
  • bA11M20.3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
cell type or tissue
0.73
transcription factor binding site profile
0.72
histone modification site profile
0.69
transcription factor perturbation
0.68


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.46   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 50   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.46   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 50   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
alkaline phosphatase measurement
2
2
1
6
69.6
C-reactive protein measurement
1
1
1
30.2
mean reticulocyte volume
1
1
1
11.8
creatinine measurement
1
1
1
5.5
glomerular filtration rate
1
1
1
5.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
alkaline phosphatase measurement
1
6
69.6
C-reactive protein measurement
1
30.2
mean reticulocyte volume
1
11.8
creatinine measurement
1
5.5
glomerular filtration rate
1
5.5
Orthologs (16)
1 – 5 of 16
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
LSM family member 14B
VGNC:6185
458382
Macaque
LSM family member 14B
700561
Mouse
MGI:3040677
241846
Rat
RGD:1563798
100362102
Dog
LSM family member 14B
VGNC:42842
485957
Species
Name
OMA
EggNOG
Inparanoid
Chimp
LSM family member 14B
Macaque
LSM family member 14B
Mouse
Rat
Dog
LSM family member 14B
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9BX40-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Protein-Protein Interactions (81)
1 – 10 of 81
SEMG2
Tbio
Novelty:  0.06325799
p_int:  0.999999954
p_ni:  4.6e-8
Score:  0.219
Data Source:  BioPlex,STRINGDB
SEMG1
Tbio
Novelty:  0.0161449
p_int:  0.99999635
p_ni:  0.00000365
Score:  0.177
Data Source:  BioPlex,STRINGDB
CHCHD2
Tbio
Novelty:  0.01615338
p_int:  0.999746938
p_ni:  0.000253062
Data Source:  BioPlex
CLEC3A
Tdark
Novelty:  0.21498836
p_int:  0.999029893
p_ni:  0.000970107
Data Source:  BioPlex
SIRT3
Tchem
Family:  Epigenetic
Novelty:  0.00101187
p_int:  0.998002835
p_ni:  0.001997165
Score:  0.234
Data Source:  BioPlex,STRINGDB
BHLHA15
Tbio
Family:  TF
Novelty:  0.02721846
p_int:  0.978570763
p_ni:  0.021429237
Data Source:  BioPlex
ICK
Tchem
Family:  Kinase
Novelty:  0.00810476
p_int:  0.97006277
p_ni:  0.000111681
p_wrong:  0.029825548
Score:  0.187
Data Source:  BioPlex,STRINGDB
GTF3C2
Tdark
Novelty:  0.1827844
p_int:  0.955387783
p_ni:  0.044612217
Score:  0.205
Data Source:  BioPlex,STRINGDB
CHCHD10
Tbio
Novelty:  0.01659548
p_int:  0.942608422
p_ni:  0.057391578
Data Source:  BioPlex
LUC7L
Tbio
Novelty:  0.05748021
p_int:  0.903122509
p_ni:  0.096877491
Data Source:  BioPlex
Publication Statistics
PubMed Score  2.46

PubMed score by year
PubTator Score  5.99

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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