Tbio BOC Brother of CDO

Protein Summary

Description

Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells. The protein encoded by this gene is a member of the immunoglobulin/fibronectin type III repeat family. It is a component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells, and promotes myogenic differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2014]

Uniprot Accession IDs

• Q9BWV1
• A6NJ30
• B2RMS8
• D3DN70
• Q6UXJ5
• Q8N2P7
• Q8NF26
• Protein BOC

Gene Name

• BOC

Ensembl ID

• ENST00000273395
• ENSP00000273395
• ENSG00000144857
• ENST00000355385
• ENSP00000347546
• ENST00000495514
• ENSP00000418663

Symbol

• CDON2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.85
PubMedID	0.76
histone modification site profile	0.75
kinase perturbation	0.66
cell type or tissue	0.54

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.31   (req: < 5)

Gene RIFs: 9   (req: <= 3)

Antibodies: 152   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.31   (req: >= 5)

Gene RIFs: 9   (req: > 3)

Antibodies: 152   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0