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Tdark
SLC4A1AP
Kanadaptin

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000326019
  • ENSP00000323837
  • ENSG00000163798
  • ENST00000613058
  • ENSP00000479964

Symbol
  • HLC3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.96
histone modification site profile
0.89
kinase perturbation
0.88
drug perturbation
0.87
transcription factor binding site profile
0.84


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.66   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 107   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.66   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 107   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (67)
PHF5A
Tbio
Family:  Epigenetic
Novelty:  0.02989472
p_int:  0.999999467
p_ni:  5.32e-7
Data Source:  BioPlex
SNRPA1
Tbio
Novelty:  0.01232044
p_int:  0.999992998
p_ni:  0.000007002
Score:  0.592
Data Source:  BioPlex,STRINGDB
SNRPE
Tbio
Novelty:  0.02033423
p_int:  0.999991627
p_ni:  0.000008367
p_wrong:  6e-9
Score:  0.359
Data Source:  BioPlex,STRINGDB
SNRPGP15
Tdark
p_int:  0.999979608
p_ni:  0.000020392
Data Source:  BioPlex
SNRPB2
Tbio
Novelty:  0.17219587
p_int:  0.999978647
p_ni:  0.000021353
Data Source:  BioPlex
RBM11
Tbio
Novelty:  0.3223316
p_int:  0.999978062
p_ni:  0.000021938
Score:  0.269
Data Source:  BioPlex,STRINGDB
SNRPN
Tbio
Novelty:  0.002157
p_int:  0.999955658
p_ni:  0.000044342
Score:  0.551
Data Source:  BioPlex,STRINGDB
RBM7
Tbio
Novelty:  0.07482689
p_int:  0.99932317
p_ni:  0.00067683
Score:  0.188
Data Source:  BioPlex,STRINGDB
TCEANC2
Tdark
Novelty:  0.40325323
p_int:  0.998675332
p_ni:  0.001324668
Score:  0.181
Data Source:  BioPlex,STRINGDB
SNRPB
Tbio
Novelty:  0.01503535
p_int:  0.993800752
p_ni:  0.006199247
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (5)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations (null)
No disease associations found
GWAS Traits (22)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
triglyceride measurement
3
7
7
97
appendicular lean mass
3
2
3
90.4
C-reactive protein measurement
1
3
3
89.3
apolipoprotein B measurement
1
2
2
71.1
serum gamma-glutamyl transferase measurement
1
1
1
70.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
triglyceride measurement
7
97
appendicular lean mass
3
90.4
C-reactive protein measurement
3
89.3
apolipoprotein B measurement
2
71.1
serum gamma-glutamyl transferase measurement
1
70.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 4 member 1 adaptor protein
VGNC:7714
459111
Macaque
solute carrier family 4 member 1 adaptor protein
701783
Mouse
MGI:1196608
20534
Rat
RGD:1307080
298805
Dog
39S ribosomal protein L33, mitochondrial [Source:RefSeq peptide;Acc:NP_001273997]
Species
Name
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 4 member 1 adaptor protein
Macaque
solute carrier family 4 member 1 adaptor protein
Mouse
Rat
Dog
39S ribosomal protein L33, mitochondrial [Source:RefSeq peptide;Acc:NP_001273997]
Publication Statistics
PubMed Score 3.66
PubMed score by year
PubTator Score 3.70
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title