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Tdark
SSBP4
Single-stranded DNA-binding protein 4

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000270061
  • ENSP00000270061
  • ENSG00000130511
  • ENST00000348495
  • ENSP00000252807
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.94
kinase perturbation
0.88
transcription factor binding site profile
0.82
virus perturbation
0.79
cell type or tissue
0.7


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.67   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 70   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.67   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 70   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte count
1
1
1
22
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte count
1
22
Gene Ontology Terms (5)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (34)
1 – 10 of 34
SSBP2
Tbio
Novelty: 0.06546999
p_int: 1
Score: 0.867
Data Source: BioPlex,STRINGDB
SSBP3
Tbio
Novelty: 0.01955714
p_int: 1
Score: 0.867
Data Source: BioPlex,STRINGDB
LMX1B
Tbio
Family: TF
Novelty: 0.00405645
p_int: 1
Score: 0.709
Data Source: BioPlex,STRINGDB
LDB1
Tbio
Novelty: 0.01110112
p_int: 0.999999989
p_ni: 1.1e-8
Score: 0.95
Data Source: BioPlex,STRINGDB
LHX4
Tbio
Family: TF
Novelty: 0.02047732
p_int: 0.999999987
p_ni: 1.3e-8
Score: 0.766
Data Source: BioPlex,STRINGDB
ISL2
Tbio
Family: TF
Novelty: 0.03917372
p_int: 0.999999985
p_ni: 1.4e-8
Score: 0.871
Data Source: BioPlex,STRINGDB
ISL1
Tbio
Family: TF
Novelty: 0.00169431
p_int: 0.999999965
p_ni: 2e-8
p_wrong: 1.5e-8
Score: 0.88
Data Source: BioPlex,STRINGDB
LMO1
Tbio
Novelty: 0.01670419
p_int: 0.999999789
p_ni: 1.82e-7
p_wrong: 2.9e-8
Score: 0.262
Data Source: BioPlex,STRINGDB
LHX6
Tbio
Family: TF
Novelty: 0.01603143
p_int: 0.999999623
p_ni: 3.74e-7
p_wrong: 3e-9
Score: 0.786
Data Source: BioPlex,STRINGDB
LHX8
Tbio
Family: TF
Novelty: 0.01815234
p_int: 0.999998124
p_ni: 8.4e-8
p_wrong: 0.000001791
Score: 0.45
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  2.67

PubMed score by year
PubTator Score  0.5

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer