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Tbio
DPCD
Protein DPCD

Protein Summary
Description
May play a role in the formation or function of ciliated cells. This gene in mouse encodes a protein that may be involved in the generation and maintenance of ciliated cells. In mouse, expression of this gene increases during ciliated cell differentiation, and disruption of this gene has been linked to primary ciliary dyskinesia. [provided by RefSeq, Jul 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000370151
  • ENSP00000359170
  • ENSG00000166171
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.9
disease perturbation
0.62
transcription factor perturbation
0.61
tissue sample
0.6
cell line
0.53


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.7   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 167   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 10.7   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 167   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
1
1
1
38.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
1
38.8
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
deleted in primary ciliary dyskinesia homolog
VGNC:3837
745109
Macaque
deleted in primary ciliary dyskinesia homolog (mouse)
712082
Mouse
MGI:4820566
Rat
RGD:1307648
294004
Dog
deleted in primary ciliary dyskinesia homolog (mouse)
477800
Species
Name
OMA
EggNOG
Inparanoid
Chimp
deleted in primary ciliary dyskinesia homolog
Macaque
deleted in primary ciliary dyskinesia homolog (mouse)
Mouse
Rat
Dog
deleted in primary ciliary dyskinesia homolog (mouse)
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9BVM2-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (8)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Protein-Protein Interactions (56)
1 – 10 of 56
RUVBL2
Tbio
Novelty:  0.01129017
p_int:  0.999999996
p_ni:  2e-9
p_wrong:  2e-9
Score:  0.854
Data Source:  BioPlex,STRINGDB
RUVBL1
Tbio
Novelty:  0.0089115
p_int:  0.99999999
p_ni:  9e-9
p_wrong:  1e-9
Score:  0.909
Data Source:  BioPlex,STRINGDB
LSM3
Tbio
Novelty:  0.05044984
p_int:  0.999998842
p_ni:  0.000001153
p_wrong:  6e-9
Data Source:  BioPlex
RABGGTA
Tdark
Family:  Enzyme
Novelty:  0.19962321
p_int:  0.992101588
p_ni:  0.006678501
p_wrong:  0.001219912
Score:  0.187
Data Source:  BioPlex,STRINGDB
FBXW4
Tbio
Novelty:  0.06255177
Score:  0.798
Data Source:  STRINGDB
POLL
Tbio
Family:  Enzyme
Novelty:  0.00244645
Score:  0.791
Data Source:  STRINGDB
DNAL4
Tbio
Novelty:  0.15546154
Score:  0.725
Data Source:  STRINGDB
DNAL1
Tbio
Novelty:  0.00168166
Score:  0.724
Data Source:  STRINGDB
DNALI1
Tbio
Novelty:  0.13865981
Score:  0.719
Data Source:  STRINGDB
LBX1
Tbio
Family:  TF
Novelty:  0.00550999
Score:  0.711
Data Source:  STRINGDB
Publication Statistics
PubMed Score  10.70

PubMed score by year
PubTator Score  4.1

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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