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Tbio
C2orf49
Ashwin

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000258457
  • ENSP00000258457
  • ENSG00000135974

Symbol
  • asw
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.48   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 136   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 26.48   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 136   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (23)
DDX1
Tchem
Family:  Enzyme
Novelty:  0.01691884
p_int:  0.999999999
p_ni:  1e-9
Score:  0.989
Data Source:  BioPlex,STRINGDB
PIN1
Tchem
Family:  Enzyme
Novelty:  0.00957198
p_int:  0.999688701
p_ni:  0.000310069
p_wrong:  0.000001231
Data Source:  BioPlex
RNASE1
Tchem
Family:  Enzyme
Novelty:  0.00198139
p_int:  0.888365266
p_ni:  0.000314504
p_wrong:  0.11132023
Score:  0.69
Data Source:  BioPlex,STRINGDB
FAM98B
Tdark
Novelty:  0.47641513
Score:  0.998
Data Source:  STRINGDB
RTRAF
Tbio
Novelty:  0.03996206
Score:  0.997
Data Source:  STRINGDB
RTCB
Tbio
Family:  Enzyme
Novelty:  0.01114311
Score:  0.996
Data Source:  STRINGDB
ZBTB8OS
Tbio
Family:  Enzyme
Novelty:  0.03929334
Score:  0.923
Data Source:  STRINGDB
FUS
Tbio
Novelty:  0.00065625
Score:  0.862
Data Source:  STRINGDB
HNRNPD
Tbio
Novelty:  0.00538829
Score:  0.85
Data Source:  STRINGDB
ZSWIM2
Tbio
Family:  Enzyme
Novelty:  0.02135835
Score:  0.836
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (3)
Metabolism of RNA (R-HSA-8953854)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of RNA
Reactome
tRNA processing
Reactome
tRNA processing in the nucleus
Name
Explore in Pharos
Explore in Source
Metabolism of RNA
tRNA processing
tRNA processing in the nucleus
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (14)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
2
1
2
59.6
age at menarche
2
2
2
57.7
body mass index
1
1
1
40.7
gait measurement
1
2
2
36.5
BMI-adjusted hip circumference
1
1
1
31.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
2
59.6
age at menarche
2
57.7
body mass index
1
40.7
gait measurement
2
36.5
BMI-adjusted hip circumference
1
31.4
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 2A C2orf49 homolog
VGNC:10436
744915
Mouse
MGI:2138299
98404
Rat
RGD:1310553
301374
Dog
chromosome 10 C2orf49 homolog
VGNC:52483
611271
Horse
chromosome 15 C2orf49 homolog
VGNC:51282
100050013
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 2A C2orf49 homolog
Mouse
Rat
Dog
chromosome 10 C2orf49 homolog
Horse
chromosome 15 C2orf49 homolog
Publication Statistics
PubMed Score 26.48
PubMed score by year
PubTator Score 10.67
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title