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Tdark
ZNF747
KRAB domain-containing protein ZNF747

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IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.06   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 76   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.06   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 76   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q9BV97-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (3)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (11)
1 – 10 of 11
GTF3C4
Tdark
Family: Epigenetic
Novelty: 0.28198123
p_int: 0.999999984
p_ni: 1.2e-8
p_wrong: 5e-9
Data Source: BioPlex
ZNF707
Tdark
Family: TF
Novelty: 1.42194815
p_int: 0.999999375
p_ni: 4.31e-7
p_wrong: 1.94e-7
Score: 0.205
Data Source: BioPlex,STRINGDB
VWCE
Tbio
Novelty: 0.09328341
p_int: 0.999999053
p_ni: 6.88e-7
p_wrong: 2.59e-7
Data Source: BioPlex
EFEMP1
Tbio
Novelty: 0.00574779
p_int: 0.999998436
p_ni: 0.000001539
p_wrong: 2.5e-8
Data Source: BioPlex
SUFU
Tbio
Novelty: 0.00475249
p_int: 0.999993551
p_ni: 0.000006449
Score: 0.398
Data Source: BioPlex,STRINGDB
MZB1
Tbio
Novelty: 0.04147497
p_int: 0.999942045
p_ni: 0.000057949
p_wrong: 6e-9
Score: 0.359
Data Source: BioPlex,STRINGDB
TRIM28
Tbio
Family: Epigenetic
Novelty: 0.00778381
p_int: 0.999541504
p_ni: 0.000458496
Score: 0.919
Data Source: BioPlex,STRINGDB
ZNF785
Tdark
Family: TF
Novelty: 0.42629766
p_int: 0.999505455
p_ni: 0.000003323
p_wrong: 0.000491222
Data Source: BioPlex
CYGB
Tbio
Novelty: 0.0005482
p_int: 0.993604919
p_ni: 0.006394998
p_wrong: 8.3e-8
Score: 0.359
Data Source: BioPlex,STRINGDB
MRS2
Tbio
Novelty: 0.00264753
p_int: 0.988470807
p_ni: 0.011529193
Data Source: BioPlex
Publication Statistics
PubMed Score  0.06

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer