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Tdark
EFCAB11
EF-hand calcium-binding domain-containing protein 11

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000316738
  • ENSP00000326267
  • ENSG00000140025
  • ENST00000538485
  • ENSP00000438072
  • ENST00000555872
  • ENSP00000452320
  • ENST00000556005
  • ENSP00000452143
  • ENST00000556609
  • ENSP00000452335
  • ENST00000556639
  • ENSP00000452397

Symbol
  • C14orf143
  • C14orf143
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
1
transcription factor binding site profile
0.83
kinase perturbation
0.71
phenotype
0.61
tissue sample
0.61


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.47   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 14   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.47   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 14   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (50)
1 – 10 of 50
CETN1
Tbio
Novelty:  0.01208917
p_int:  0.999999918
p_wrong:  8.2e-8
Score:  0.35
Data Source:  BioPlex,STRINGDB
FNTB
Tclin
Family:  Enzyme
Novelty:  0.07434994
Score:  0.647
Data Source:  STRINGDB
MYH10
Tchem
Novelty:  0.00624251
Score:  0.634
Data Source:  STRINGDB
ZC3H14
Tbio
Novelty:  0.07532778
Score:  0.608
Data Source:  STRINGDB
OBSCN
Tbio
Family:  Kinase
Novelty:  0.01173699
Score:  0.601
Data Source:  STRINGDB
SPEG
Tbio
Family:  Kinase
Novelty:  0.01666376
Score:  0.601
Data Source:  STRINGDB
GPR65
Tbio
Family:  GPCR
Novelty:  0.02341854
Score:  0.572
Data Source:  STRINGDB
CLVS2
Tbio
Novelty:  0.95264322
Score:  0.567
Data Source:  STRINGDB
LRRN3
Tbio
Novelty:  0.06491104
Score:  0.566
Data Source:  STRINGDB
STYXL1
Tbio
Family:  Enzyme
Novelty:  0.12806983
Score:  0.546
Data Source:  STRINGDB
Gene Ontology Terms (10)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
InterPro
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
2.2
46.1
1
1
0
2.3
36.5
QT interval
1
1
2
1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
2.2
46.1
0
2.3
36.5
QT interval
2
1
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
EF-hand calcium binding domain 11
VGNC:3440
453095
Macaque
EF-hand calcium binding domain 11
695233
Mouse
MGI:1926017
78767
Rat
RGD:1565006
500705
Dog
EF-hand calcium binding domain 11
VGNC:40213
480414
Species
Name
OMA
EggNOG
Inparanoid
Chimp
EF-hand calcium binding domain 11
Macaque
EF-hand calcium binding domain 11
Mouse
Rat
Dog
EF-hand calcium binding domain 11
Publication Statistics
PubMed Score 1.47
PubMed score by year
PubTator Score 1.07
PubTator score by year